Latest reports say at least seven Palestinians, most of them women and children, were killed in the latest attacks on Wednesday, bringing the death toll to 35 since Tuesday.
Local residents and witnesses say several residential buildings have been targeted in the attacks.
Nearly 300 people have been also injured in air raids on the impoverished territory.
This comes as Tel Aviv is also taking steps towards a ground incursion into the coastal sliver.
The Health Ministry in the occupied Palestinian territories has announced a state of emergency in all its medical facilities.
A spokesman for Hamas resistance movement has described the attack a massacre of children and a horrendous war crime.
Following the Israeli military's attack on residential areas and civilian targets in the southern city of Khan Yunis, Hamas officials said all Israelis are now legitimate targets.
Palestinian resistance movements in the besieged Gaza Strip have responded to Israel’s aggression by targeting towns and cities deep inside the occupied Palestinian territories. The Israeli military said on Tuesday that 130 rockets were fired from Gaza, with 70 hitting different sites.
Israel keeps killing Palestinians in the besieged Gaza Strip as the United States says Tel Aviv has every right to attack Gaza.
The President of the Palestinian national unity government, Mahmoud Abbas, has demanded an immediate end to Israel’s offensive against Gaza amid continued airstrikes.
Gaza has been blockaded since June 2007, which is a situation that has caused a decline in the standard of living, unprecedented levels of unemployment, and unrelenting poverty.